The melanoma update is deliberately narrow: how prospective CP-GEP data may inform the sentinel-node conversation, what 10-year CheckMate 067 follow-up says about the durability of modern immunotherapy, and how RP1 plus nivolumab expands the post–PD-1 treatment landscape.
Three themes
Predict better
MERLIN_001 provides prospective, blinded evidence on CP-GEP as a tool to refine sentinel-node risk assessment.
Appreciate the durability
CheckMate 067 at 10 years shows how long-term survival has become a defining feature of metastatic melanoma treatment.
Add an option after PD-1
RP1 plus nivolumab introduces a newly approved oncolytic-immunotherapy option for selected PD-1–refractory advanced melanoma.